How does the sensitivity of proteins to lipid composition and membrane shape affect cell organization, antimicrobial peptide activity, and protein function? Find out HERE.
How protein self-assembly leads to the formation of membranes pores, liquid droplets, or amyloid structures? Find out HERE.
These are two major questions we address using computer simulations and theory. We develop and apply new computational models and methods with a multiscale approach that can explain and predict complex phenomena occurring in biomolecular systems. We focus on protein-membrane and protein-protein interactions that regulate cellular signaling, transport, virus infection, and our immune system, and are thus linked to a number of deadly diseases ranging from cancer to Alzheimer’s disease.