About

We are a world-leading interdisciplinary team focused on the de novo design of membrane-active peptides, with a special emphasis on peptide therapeutics. Our design strategy is guided by a deep understanding of the molecular mechanisms underlying essential biological processes, as well as by their potential applications in medicine, biochemistry, and biotechnology. We develop and use advanced theoretical and computational tools for multiscale modeling, spanning all-atom simulations to highly coarse-grained representations with a single particle per molecule. To ensure biological relevance, we validate our computational predictions through experiments conducted in our laboratory. Our motto is: “Improving the well-being of humankind by understanding peptide–membrane interactions.”

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erc msmt npo eu gacr it4i metacentrum